Medication error: Subarachnoid injection of tranexamic acid

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Tranexamic acid (AMCA) in aneurysmal subarachnoid haemorrhage.

Subarachnoid haemorrhage due to a ruptured cerebral aneurysm is a dramatic event in neurosurgery and one of the most destructive. Its management is complicated by the risks of rebleeding and cerebral vasospasm and their sequelae. Rebleeding and vasospasm rarely occur before three days after the primary bleed.'2 Angiographic vasospasm is seen most often 10 to 17 days after bleeding.3 Because of ...

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Accidental Intrathecal Injection of Tranexamic Acid

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Tranexamic acid in subarachnoid hemorrhage. A double-blind study.

The effects of intravenous tranexamic acid were compared with placebo in 64 patients with subarachnoid hemorrhage. A double-blind procedure was used. One gram of tranexamic acid was given intravenously every 4 hours up to the time of operation on an intracranial arterial aneurysm or for up to 21 days after the first bleeding if operative treatment was not feasible. There were no differences in ...

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Short-term tranexamic acid treatment in aneurysmal subarachnoid hemorrhage.

Antifibrinolytic treatment for 4 weeks after a subarachnoid hemorrhage has been shown to have no effect on outcome since a reduction in the rate of rebleeding was offset by an increase in ischemic events. To determine if a shorter course (4 days) of antifibrinolytic treatment before the expected onset of ischemic complications might reduce the rate of rebleeding yet avoid ischemic complications...

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ژورنال

عنوان ژورنال: Indian Journal of Anaesthesia

سال: 2012

ISSN: 0019-5049

DOI: 10.4103/0019-5049.96335